This course is the advanced course of molecular biology. It is designed to introduce the genome sequences and their functions of certain organisms, so it is also the basic course of genomic science research. The content includes techniques of molecular biology, mapping techniques, sequencing strategy and methods, gene expression analysis, sequence analysis methods, high-throughput genetics, proteomics, structural genomics, genome structure, microbial genomics, comparative genomics, human genome, signal transduction, pharmaceutical applications, pharmacogenomics, disease diagnosis, agriculture applications, and ethical issues and regulations.