Traditionally, aquatic animal nutrition focused on improving growth performance of aquatic animals. It always ignored the influence on health, meat quality, as well as environment impact and disease management of aquatic animals. Different from traditional feeds, besides growth enhancement, the feeds used to enhance immunity, reproduction or specific physiological functions are namely “functional feed”. For this issue, special feed additives play an important role. This course will introduce three kinds of special feed additives, including (1) improve fish and shrimp health and physiology; (2) improve quality, such as meat quality, appearance or nutritional values; (3) enhance intestinal health to improve feed utilization and decrease ammonium/nitrogen excretion. Aquafeed with additional function can promise the product value for seafoods.